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Conclusion In case of normal FVC and by comparing both groups of
RVD and non-RVD, there were significant differences in
L’asthme constitue un véritable problème de santé terms of FVC, RV, FRC, DLCO, alveolar volume which
publique, le bon suivi et l’éducation thérapeutique sont were lower in the group with RVD and dyspnea which
un pilier essentiel pour contrôler cette maladie was higher in the same group. There were no
chronique. differences in anthropometric data as well as smoking

intensity in both groups.
P117 THE ROLE OF SPIROMETRY
IN EXCLUDING A RESTRICTIVE Conclusion :
VENTILATORY DEFECT The ATS/ERS guideline that a normal FVC excludes a
restriction should not be universally applied,
B. BARKOUS1,2, F. GUEZGUEZ1,2, N. LAZREG1, M. particularly in Tunisian population. In our sample a cutoff
ABDESSLEM1, A. SAYHI1,2, I. GHANNOUCHI1,2, S. value of FVC z-score at “-0.835” could exclude
ROUATBI1,2 restriction with a good specificity. In this case,
1 DEPARTMENT OF PHYSIOLOGY AND FUNCTIONAL EXPLORATIONS, restriction seems to start with a decrease of RV while
UNIVERSITY HOSPITAL OF FARHAT HACHED, SOUSSE, TUNISIA. 2 conserving a normal FVC.
RESEARCH LABORATORY OF HEART FAILURE, LR12SP09
Introduction: P118 CORRELATION BETWEEN

According to ATS/ERS latest guidelines (2022), 6 MINUTE WALK TEST AND
spirometry can usually exclude a Restrictive Ventilatory SPIROMETRY IN A HEALTHY
Defect (RVD) when the forced vital capacity (FCV) is POPULATION
normal. However, it remains a controversial issue.
B. BARKOUS 1,2, I. GHANNOUCHI1,2, A. SAYHI1,2, F.
Aims:
GUEZGUEZ1,2, H. BEN SAAD1,2, S. ROUATBI1,2
To determine the predictive values of the FVC in 1 DEPARTMENT OF PHYSIOLOGY AND FUNCTIONAL EXPLORATIONS,
diagnosing a RVD and to investigate clinical and UNIVERSITY HOSPITAL OF FARHAT HACHED, SOUSSE, TUNISIA. 2,
functional features of subjects with RVD while having a RESEARCH LABORATORY OF HEART FAILURE, LR12SP09
normal FVC. Introduction:
Patients and methods: The 6 Minute Walk Test (6MWT) is an exercise test used
as a clinical indicator of the functional capacity in
It was a retrospective study conducted in the patients with cardiopulmonary diseases.
department of physiology and functional explorations
of the university hospital Farhat HACHED of Sousse. It Aim:
included 155 patients who underwent complete
pulmonary function testing using Medisoft body box The aim of the study was to investigate the correlation
plethysmograph. FVC, Functional Residual Capacity between different spirometric variables and 6MWD
(FRC), Residual Volume (RV) and Total Lung Capacity variables such as 6 Minute Walk Distance (6MWD) and
(TLC) were determined, and their respective z-scores Heart Rate (HR).
were calculated according to the GLI norms for Patients and methods:
spirometric data (2012) and static lung volumes (2021). A
z-score greater than ""-1.645"" was considered normal. It was a retrospective study, conducted in the
department of physiology and functional explorations
Results: of the university hospital Farhat HACHED of Sousse,
Among the 155 patients included, 41.9% had a RVD (ie, z- during 2019-2020, including 229 healthy subjects. All
score of TLC below « -1.645 »). Mean values of age participants performed spirometry with measurement
(years) and BMI (kg/m2) were 56±12 and 15±14, of FEV1, FVC, FEF25-75 and PEF and the 6MWT according
respectively. The FVC was normal in 17 patients with a to the ATS/ERS recommendations. These parameters
RVD. ROC analysis was conducted and indicated an were collected during the 6MWT: 6MWD, HR, Oxygen
optimal cutoff value of FVC z-score for identifying RVD Saturation (OS), Systolic Blood Pressure (SBP) and
at “-0.835”, with a sensitivity and a specificity of 61% and Diastolic Blood Pressure (DBP) before and after the test.
90%, respectively, (area under the curve [AUC] = 0.817 Delta HR was calculated as follows: Maximal HR – HR at
(95% CI 0.733-0.9, p < 10-3). rest.
Results:

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